Avram Grant has named his first Chelsea team and it will line-up in a 4-3-3 formation.
Joe Cole and Florent Malouda will flank Andriy Shevchenko in attack and there are returns in defence for Paulo Ferreira and Tal Ben-Haim.
John Mikel Obi makes his 50th appearance for the Blues.
Manchester United will be spearheaded by Carlos Tevez who is playing in front of a line consisting of Cristiano Ronaldo, Ryan Giggs and Wayne Rooney.
Chelsea will line-up in a 4-3-3 formation as follows:
1 Petr Cech
20 Paulo Ferreira
22 Tal Ben-Haim
26 John Terry (c)
3 Ashley Cole
12 John Mikel Obi
4 Claude Makelele
5 Michael Essien
10 Joe Cole
7 Andriy Shevchenko
15 Florent Malouda
Substitutes: 23 Carlo Cudicini, 33 Alex, 24 Shaun Wright-Phillips, 21 Salomon Kalou, 14 Claudio Pizarro.
Man United are expected to line-up in the following 4-2-3-1 formation:
Van der Sar; Brown, Ferdinand (c), Vidic, Evra; Carrick, Scholes; Ronaldo, Giggs, Rooney; Tevez.
Subs: Kuszczak, Pique, O'Shea, Nani, Saha.
The referee is Mike Dean.
