Striker Louis Saha is available after a knee injury after but right-back Gary Neville and left-back Mikael Silvestre remain sidelined.
Arsenal defenders Kolo Toure and Emmanuel Eboue are available after their Africa Cup of Nations stint.
But Theo Walcott (thigh), Gael Clichy (hamstring) and Bacary Sagna (personal reasons) are set to miss out, while Philippe Senderos (knee) is a doubt.
Man Utd (from): Van der Sar, Kuszczak, Brown, O'Shea, Simpson, Ferdinand, Vidic, Evra, Fletcher, Nani, Park, Scholes, Ronaldo, Anderson, Carrick, Hargreaves, Giggs, Tevez, Rooney, Saha, Welbeck.
Arsenal (from): Lehmann, Fabianski, Senderos, Hleb, Fabregas, Flamini, Adebayor, Eduardo, Bendtner, Traore, Song, J Hoyte, Gilberto, Gilbert, Randall, G Hoyte, Lansbury.
